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International Journal of Computational Bioinformatics and In Silico Modeling
2013: Volume-2 Issue-5
ISSN: 2320-0634

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ABSTRACT   REFERENCES  
International Journal of Computational Bioinformatics and In Silico Modeling 2(5) 2013: 234-238

SNP analysis in core mitochondrial genes of Chlorophytes


Himani Kuntal and Vinay Sharma*

Banasthali University, Banasthali- 304022, Rajasthan, India .

* Corresponding Author

ABSTRACT

Single nucleotide polymorphisms (SNPs) represent the most frequent type of genetic polymorphism and thus provide a high density of markers near the locus of interest. However, the mining of SNPs for their and significance of SNPs in organellar genomes has not been completely understood. In the present work, mitochondrial genomes were investigated for the distribution and pattern of SNPs. In recent past, the availability of organelle genome sequences has allowed us to understand the organization of SNPs in their genic and intergenic region. Most of the SNPs in mitochondrial genes are neutral with respect to protein structure therefore can be used to study divergence in closely related species. In this study, the SNPs were identified and categorized in six mitochondrial genes of five species of class Chlorophyceae of green algae and many of their properties such as DNA polymorphism, codon usage bias, conserved DNA regions, indels etc. were measured. The data revealed that nad2 gene exhibited highest degree of polymorphism and significantly the indels were also observed in great amount in same. This work constitutes the first report of an exhaustive comparison of mitochondrial SNPs in algal species and has revealed important information thereon.


Copyright © 2013 | AIZEON publishers | All rights reserved

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Citation: Himani Kuntal and Vinay Sharma. (2013). SNP analysis in core mitochondrial genes of Chlorophytes Int J Comput Bioinfo In Silico Model 2(5): 234-238

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